Dr Pickart mentioned somewhere that Glucosamine does much the same as MSM so I was wondering if there is much benefit in taking both together. Was just reading this interesting study on Glucosamine HCL:
Abstract;A placebo-control double-blind study of long-term intake of glucosamine hydrochloride (1500mg/day for 6 weeks) was conducted in 32 women who usually tend to have dry and rough skin. The following findings were obtained: (1) Examination by dermatologists indicated that glucosamine hydrochloride significantly improved dryness of the skin, easiness to apply make-up, and exfoliation. (2) Determination of the moisture content in the skin revealed that glucosamine hydrochloride increased the moisture content in the skin. (3) Microscopic skin surface analysis showed that glucosamine hydrochloride improved smoothness and scaliness of the skin. These findings suggested that long-term intake of glucosamine hydrohloride is effective in improving moisture content and smoothness of the skin. (author abst.)http://sciencelinks.jp/j-east/article/200113/000020011301A0563646.php

Because of its stimulation of hyaluronic acid synthesis, glucosamine has been shown to accelerate wound healing, improve skin hydration, and decrease wrinkles. In addition, as an inhibitor of tyrosinase activation, it inhibits melanin production and is useful in treatment of disorders of hyperpigmentation.
http://www.blackwell-synergy.com/doi/abs/10.1111/j.1473-2165.2006.00277.x