Make Up Artists Choice has two new products that have mandelic acid in them. I was interested in purchasing them and remembered it was on the not recommended list. Under the product detail, it says that mandelic acid is derived from bitter almonds. I was just wondering if you would check these products out and tell me your opinion.

MUAC Radiance Peel
Acne Pore Minimizer With Sepicontrol A5

Thank You
Dawn

Mandelic acid is an artificial acid and is patented for various skin are uses. It also is neurotoxic and can induce adverse effects on the peripheral nervous system and produce toxic peripheral neuropathy at very low levels.

Material Safety Data Sheet

S-(+)-Mandelic acid MSDS Section

1: Chemical Product and Company Identification Product

Name: S-(+)-Mandelic acid

Information:Sciencelab.com,

Effects:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant, permeator), of eye contact(irritant), of inhalation.

Potential Chronic Health Effects:CARCINOGENIC EFFECTS: Not available.MUTAGENIC EFFECTS: Not available.TERATOGENIC EFFECTS: Not available.DEVELOPMENTAL TOXICITY: Not available.The substance is toxic to mucous membranes.Repeated or prolonged exposure to the substance can produce target organs damage.

Skin Contact:After contact with skin, wash immediately with plenty of water. Gently and thoroughly wash the contaminated skinwith running water and non-abrasive soap. Be particularly careful to clean folds, crevices, creases and groin.Cold water may be used. Cover the irritated skin with an emollient. If irritation persists, seek medical attention.Wash contaminated clothing before reusing.

Serious Skin Contact: Allow the victim to rest in a well ventilated area. Seek immediate medical attention.

Chronic Effects on Humans: The substance is toxic to mucous membranes.Other Toxic Effects on Humans:Hazardous in case of ingestion. Slightly hazardous in case of skin contact (irritant, permeator), of inhalation.

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from http://www.chemcas.com/msds/cas/msds75/8015-54-1.asp

* ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose


from http://www.chemcas.com/msds/cas/msds75/8015-54-1.asp

* ACUTE TOXICITY DATA **

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human
DOSE/DURATION : 40 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - visual field changes
Behavioral - hallucinations, distorted perceptions
Gastrointestinal - nausea or vomiting
REFERENCE :
JNMDAN Journal of Nervous and Mental Disease. (Williams & Wilkins Co., 428
E. Preston St., Baltimore, MD 21202) V.3- 1876- Volume(issue)/page/year:
131,428,1960

.....................
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Human - man
DOSE/DURATION : 150 ug/kg
TOXIC EFFECTS :
Behavioral - hallucinations, distorted perceptions
REFERENCE :
FEPRA7 Federation Proceedings, Federation of American Societies for
Experimental Biology. (Bethesda, MD) V.1-46, 1942-87.
Volume(issue)/page/year: 32,250,1973

TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Human
DOSE/DURATION : 100 ug/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
Behavioral - hallucinations, distorted perceptions
REFERENCE :
85IVAW "Possible Long-Term Health Effects of Short-Term Exposure to Chemical
Agents," National Research Council, 3 vols., Washington, DC, National
Academy Press, 1982-85 Volume(issue)/page/year: 1,L1,1982

Neurophysiological Changes in Rats
Subchronically Treated with Styrene or Its Metabolite, Junichi M,
Megumi N, Wenyuan Z, Kazuo A, J Occup Health 2000; 42: 328–335. It is
also being tested as a sperm inactivator and preservative.

We do not recommend its use.