acell.com - I have mentioned their stuff before. I obtained a small sample of their powdered product. Bottom line...

strong tca then small amount of powder mixed with emu oil and covered with healing film = stretch mark totally healed.

This is a much better method than the sucessful one I outlined in a previous post and I think this is likely to work for a much broader range of people. Problem is obtaining product from acell as their current product is vet grade and I'm not sure they sell to just anyone. The sample I obtained I got via a contact who sadly cannot provide more.

Update: They will not sell to non-vets. The 'human' formulation will not be out for a few years, even though there's no difference, aside from where it's manufactured.

This message has been edited. Last edited by: katherinesmith,

It's a ridiculous policy, but I'm sure there is a way around it.

The mark I tested this on was the worst one i had, the defect felt so deep and the skin so compromised that I was reluctant to be to harsh with it. When I managed to source some of acell's stuff I thought I would go for it. Acell could make billions if they can package this up as something that the average Jane or Joe can use at home for removing scars and preventing their formation.

My sample came from a contact that works in a vet office, but i doubt i will be able to obtain more from this source.

The way this stuff works requires that the area to be treated be open, you can't just put it on closed skin. This is where the TCA comes in to prep the area to be treated and the emu oil as well as providing a base for the powder also carries it into the skin. Resolution of treated area is complete. The healed length is like baby skin, and this is consistent with what others have reported. It's like the cellular clock has been reset in that area. Regarding price it should be inexpesnive in terms of production, but not sure what it will actually cost as an end product. It's not actually all that complex to produce, maybe an enterprising biomed student will step forward.

Was any of this Acell stuff used in the post you made about complete stretch mark resolution, or did you get rid of some more stretch marks using this different method?

Other method is very painful and depending on your skin type could leave you with serious hyperpigmentation ot worse. If you have skin that reacts badly to harsh treatments then this method should be avoided. Acell powder method is much more gentle and I think it will work for a wider range of people. Pending further feedback I'd like to investigate a way we can get this stuff in quantity.

Let me know when you get your stuff. If you can photo document each step we'll have something that others can see.

can you share with us how were u able to get a hold of Acell?

Hi

I contacted them via email when Edward first mentioned the product, they emailed me back saying they did not think it would be suitable for stretch marks. I am going to try and purchase some from a vets and try it. I saw the pictures of healing on their website too and the pictures were absolutely amazing. Very rapid healing of very deep wounds on animals. I asked them if they thought needling or something similar could drive it down through to the dermis for stretch mark sufferers but they didn't seem convinced.

Thanks Edward, you are proving to be an invaluable source of info.

J

Hi, J

Did they say why they didn't think it would be suitable?

Thanks,
Kate

They said it wouldn't penetrate as you need an open wound, however, I was already thinking along the lines of dermaroller and emu oil, much like Edward. I don't see any reason why using those two couldn't carry it to some degree through to the dermis.

Please let us know how you get on when you get your supply. It's frustrating to know that this could be a cure, but that it is not available for us to try.

Good luck!

J

We believe ACell will be an effective treatment for scars but it will require removal of the scar tissue. We hope to investigate this further once our product is available.



We will post news of product availability and research updates on our web site.
Best regards,



Mike Manning
Technical & Customer Services
ACell, Inc.
800-826-2926
www.acell.com

this is the reply i recieved a few months back

The SRCPs and Acell may be fundamentally the same process.

SRCPs are created by the breakdown of the extracellular matrix. The human remodeling factor, GHK, is a normal constituent of human plasma, saliva, and urine, The molecule has a very high affinity for copper 2+ and forms the chelate GHK-Cu. In plasma, the plasma level is about 200 ng/ml (10-7 M ) at age 20 but declines to 80 ng/ml by age 60. L. Pickart, In Vitro 17, 459, (1981); L. Pickart L. and S. Lovejoy. S., Methods Enzymol. 147, 314 (1987); L. Pickart, Cosmetics & Toiletries 118, 24 (2003), L. Pickart L, Cosmetics & Medicine (Russia) 2, 14 (2004)[4-7]

GHK is generated during proteolytic degradation of proteins of the extracellular matrix after tissue injury and probably during normal tissue turnover. Maquart et al first pointed out that while the sequence GHK is a relatively rare sequence in most proteins since its presence in a protein creates a copper binding site, the sequence is relatively high in proteins of the extracellular matrix, especially SPARC (secreted protein acidic and rich in cysteine), a protein that regulates endothelial cell shape and function during repair processes. E.H. Sage and R.B. Vernon, J. Hypertens. Suppl. 12, S145 (1994); F X. Maquart, L. Pickart, M. Laurent, P. Gillery, J. C. Monboisse and J.P. Borel, FEBS Lett. 238, 343 (1988)

You probably would get the same action by removing the scar tissue with the strong TCA peel, then using Trireduction or Super Cop.

Dr Pickart

Is there no possibility of your collaborating with acell as a distributor, or producing something similar yourself? I believe its derived from pigs bladder, which is not a new treatment as this was used for centuries during wars etc to treat wounds. It seems to be a bit of a forgotten treatment that has been rediscovered. It certainly seems to produce a rapid response which is the key here and makes it far more viable than other treatments.

It might be prudent to get into this area in the early stages.

J

Dr. Pickart,

Do you think results would be as quick as Edward claims to have w/ Acell by doing a strong
glycolic acid peel a few times a week followed by 2x super Cop?
Thanks
MP

The Acell system uses a very strong TCA peel to remove the scar tissue. This may be a key.

The SRCPs (skin remodeling copper peptides) are produced from matrix proteins and have the perfect biochemistry for scar reduction and tissue remodeling.

GHK is called a "matrikine", that is, a molecule produced by the breakdown of extracellular matrix material.

Hi Edward and everyone!

Edward, that's amazing! Two questions for you:

1. How long did it take you to heal the mark, start to finish?

2. How long did you wear the bandage?

quote:

Originally posted by Dr. Pickart:
The Acell system uses a very strong TCA peel to remove the scar tissue. This may be a key.

The SRCPs (skin remodeling copper peptides) are produced from matrix proteins and have the perfect biochemistry for scar reduction and tissue remodeling.

GHK is called a "matrikine", that is, a molecule produced by the breakdown of extracellular matrix material.

Doctor Pickart,

You refer to the the Acell "system" here. Now is this an actual procedure that is outlined in the instructions for the product or are you recalling the method by which Edward Nigma has rid himself of the stretch mark?

The Acell system is a two step system.

The first is removing the scar tissue, which we have alway emphasized. They use a strong TCA acid and essentially dissolve the scar tissue.

The second step is using the extract of extracellular matrix to stimulate the production of new skin. This may be similar to the use of GHK, since GHK is produced by the breakdown of the extracellular matrix after wounding.

Thanks. So which of your products would you recommend to substitute on top of the GHK? Should I get the serum or the cream for my SM's? Obviously the Emu Oil S. Anything else to follow up the TCA peel?